Costantino Pitzalis Selected Research

Tertiary Lymphoid Structures

12/2019	Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis.
1/2019	B cells in the formation of tertiary lymphoid organs in autoimmunity, transplantation and tumorigenesis.
10/2015	Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.
4/2014	EBV and other viruses as triggers of tertiary lymphoid structures in primary Sjögren's syndrome.
9/2010	Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets.

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Costantino Pitzalis Research Topics

Disease

64	Rheumatoid Arthritis 11/2022 - 11/2002
39	Inflammation (Inflammations) 05/2022 - 11/2002
29	Arthritis (Polyarthritis) 11/2022 - 04/2005
11	Synovitis 03/2021 - 03/2015
10	Osteoarthritis 11/2021 - 01/2006
8	Necrosis 01/2021 - 09/2014
8	Neoplasms (Cancer) 01/2021 - 11/2007
6	Psoriatic Arthritis 01/2021 - 04/2004
5	Autoimmune Diseases (Autoimmune Disease) 02/2021 - 04/2006
5	Tertiary Lymphoid Structures 12/2019 - 09/2010
4	Disease Progression 11/2021 - 09/2011
4	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2020 - 02/2010
4	Sialadenitis 01/2020 - 01/2004
4	Fatigue 01/2017 - 01/2014
3	Peritonitis 01/2022 - 01/2013
3	Experimental Arthritis 12/2019 - 12/2010
3	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 10/2016 - 01/2009
3	Lymphoma (Lymphomas) 08/2012 - 01/2008
3	Ankylosing Spondylitis 11/2010 - 04/2009
2	Rheumatic Diseases (Rheumatism) 01/2021 - 01/2015
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 01/2016
2	Infections 01/2020 - 09/2015
2	Pain (Aches) 01/2020 - 01/2016
2	Arthralgia (Joint Pain) 01/2018 - 01/2017
2	Multiple Sclerosis 01/2017 - 04/2006
2	Sjogren's Syndrome (Sjogren Syndrome) 01/2017 - 08/2012
2	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 01/2008 - 10/2007
1	Acquired Immunodeficiency Syndrome (AIDS) 02/2021
1	Lupus Nephritis 01/2021
1	Nephritis 01/2021
1	Proteinuria 01/2021
1	Pneumonia (Pneumonitis) 01/2020
1	Cushing Syndrome 01/2020

Drug/Important Bio-Agent (IBA)

17	CytokinesIBA 03/2021 - 11/2002
11	Biological ProductsIBA 01/2021 - 11/2007
11	AutoantibodiesIBA 01/2020 - 11/2008
10	AntigensIBA 01/2020 - 07/2006
9	RNA (Ribonucleic Acid)IBA 11/2022 - 09/2013
9	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2008
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2009
7	Antirheumatic Agents (DMARD)IBA 11/2022 - 07/2016
7	LigandsIBA 01/2021 - 04/2008
7	AntibodiesIBA 12/2018 - 04/2011
7	Peptides (Polypeptides)IBA 10/2016 - 11/2010
6	Rituximab (Mabthera)FDA Link 01/2022 - 01/2008
6	Pharmaceutical PreparationsIBA 02/2021 - 08/2014
6	ChemokinesIBA 01/2018 - 04/2008
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 01/2008
4	Interleukin-1 (Interleukin 1)IBA 11/2021 - 04/2011
4	Interleukin-6 (Interleukin 6)IBA 12/2020 - 12/2010
4	LipidsIBA 10/2020 - 01/2013
4	Tumor Necrosis Factor InhibitorsIBA 01/2020 - 09/2014
3	Messenger RNA (mRNA)IBA 01/2022 - 11/2009
3	Interleukin-17 (Interleukin 17)IBA 01/2020 - 04/2009
3	InterferonsIBA 01/2020 - 01/2016
3	Interleukin-27 (Interleukin 27)IBA 01/2020 - 10/2015
3	Lactic Acid (Lactate)FDA LinkGeneric 12/2019 - 07/2015
3	Monoclonal AntibodiesIBA 01/2018 - 09/2014
2	Methotrexate (Mexate)FDA LinkGeneric 11/2022 - 01/2018
2	ZymosanIBA 01/2022 - 01/2013
2	tocilizumab (atlizumab)FDA Link 01/2022 - 01/2021
2	Small Cytoplasmic RNAIBA 01/2022 - 01/2019
2	EnzymesIBA 11/2021 - 01/2009
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 01/2018
2	Interleukin-23 (Interleukin 23)IBA 01/2021 - 04/2009
2	Adalimumab (Humira)FDA Link 01/2021 - 10/2015
2	Therapeutic UsesIBA 01/2021 - 04/2006
2	GlucocorticoidsIBA 01/2020 - 11/2012
2	serum P-component (CIt)IBA 01/2018 - 10/2016
2	InterleukinsIBA 08/2017 - 07/2003
2	AutoantigensIBA 10/2016 - 09/2013
2	Lymphotoxin-alpha (Lymphotoxin)IBA 10/2016 - 01/2016
2	Interleukin-18 (Interleukin 18)IBA 04/2011 - 01/2004
2	Cytidine DeaminaseIBA 01/2009 - 10/2007
1	AutacoidsIBA 05/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Complement System Proteins (Complement)IBA 01/2022
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 11/2021
1	KN 93IBA 11/2021
1	CalciumIBA 11/2021
1	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 11/2021
1	iberdomideIBA 01/2021
1	c-Mer Tyrosine KinaseIBA 01/2021
1	Immunoglobulin G (IgG)IBA 01/2021
1	CreatinineIBA 01/2021
1	Ustekinumab (CNTO 1275)FDA Link 01/2021
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2021
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2021
1	interleukin-21 (interleukin 21)IBA 12/2020
1	Interleukin-8 (Interleukin 8)IBA 12/2020
1	Connective Tissue Growth FactorIBA 01/2020
1	Metformin (Glucophage)FDA LinkGeneric 01/2020
1	Receptor Tyrosine Kinase-like Orphan ReceptorsIBA 01/2020
1	Protein-Arginine DeiminasesIBA 12/2019
1	Interleukin-10 (Interleukin 10)IBA 11/2019

Therapy/Procedure

32	Therapeutics 11/2022 - 04/2004
6	Biological Therapy 01/2022 - 12/2010
2	Aftercare (After-Treatment) 01/2020 - 01/2020
2	Intra-Articular Injections 01/2017 - 11/2015
1	Precision Medicine 02/2021